P-176 Epigenetic Regulation of Inflammation in IL-10-/- Mouse
نویسندگان
چکیده
منابع مشابه
P-176: Infertility and Smoking
Background: Approximately 30% of reproductive age women and 35% of reproductive age men in the United States smoke cigarettes. Substantial harmful effects of cigarette smoke on fecundity and reproduction have become apparent but are not generally appreciated. smoking is becoming increasingly popular in many parts of the world as in eastern Mediterranean and Arabic countries including Iran. The ...
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Antigen-presenting cells are thought to modulate the development of Th1 and Th2 cells by the secretion of interleukin-10 (IL-10) and IL-12. Because glucocorticoids (GC) favor the development of Th2 responses, we determined whether dexamethasone (DEX) and hydrocortisone (HC) have differential effects on lipopolysaccharide-induced IL-10 and IL-12 production in whole-blood cultures. Significant in...
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Turnover of the extracellular matrix (ECM), activation of macrophages, and accumulation of chemokines/cytokines are all hallmarks of chronic inflammation. Extracellular matrix components, such as hyaluronan (HA), have recently been shown to influence macrophage effector functions, such as the release of inflammatory chemokines and cytokines. Although low m.w. fragments of the glycosaminoglycan ...
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ژورنال
عنوان ژورنال: Inflammatory Bowel Diseases
سال: 2014
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000456895.92482.9d